Liver Cancer Trial

Vicus is evaluating VT-122, a novel investigational combination of etodolac and propranolol, and Nexavar® (sorafenib) tablets, in a Phase 2 trial as a potential new treatment option for patients with advanced liver cancer (hepatocellular carcinoma), systemic inflammation and cachexia.

The randomized, open label, multi-center Phase 2 study will evalutate whether VT-122 in combination with Nexavar increases “Clinical Benefit Response,” which is a composite measurement of pain, performance status, and lean body mass, as compared to Nexavar alone. The secondary efficacy endpoints of this study are cancer and cachexia specific symptoms, duration of Nexavar therapy and overall survival. The study will be conducted under Vicus’ US IND and is expected to enroll 80 patients with advanced liver cancer, systemic inflammation and cachexia at multiple sites in the United States. Enrollment into this study is expected to be completed by the end of 2012.

For more information about enrolling in the study, please visit www.clinicaltrial.gov.